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Conjugation of Hot-Melt Extrusion with High-Pressure Homogenization: a Novel Method of Continuously Preparing Nanocrystal Solid Dispersions

Over the past few decades, nanocrystal formulations have evolved as promising drug delivery systems owing to their ability to enhance the bioavailability and maintain the stability of poorly water-soluble drugs. However, conventional methods of preparing nanocrystal formulations, such as spray dryin...

詳細記述

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書誌詳細
出版年:AAPS PharmSciTech
主要な著者: Ye, Xingyou, Patil, Hemlata, Feng, Xin, Tiwari, Roshan V., Lu, Jiannan, Gryczke, Andreas, Kolter, Karl, Langley, Nigel, Majumdar, Soumyajit, Neupane, Dipesh, Mishra, Sanjay R., Repka, Michael A.
フォーマット: Artigo
言語:Inglês
出版事項: Springer US 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4766117/
https://ncbi.nlm.nih.gov/pubmed/26283197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-015-0389-7
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