Conjugation of Hot-Melt Extrusion with High-Pressure Homogenization: a Novel Method of Continuously Preparing Nanocrystal Solid Dispersions

Over the past few decades, nanocrystal formulations have evolved as promising drug delivery systems owing to their ability to enhance the bioavailability and maintain the stability of poorly water-soluble drugs. However, conventional methods of preparing nanocrystal formulations, such as spray dryin...

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Detalhes bibliográficos
Publicado no:AAPS PharmSciTech
Main Authors: Ye, Xingyou, Patil, Hemlata, Feng, Xin, Tiwari, Roshan V., Lu, Jiannan, Gryczke, Andreas, Kolter, Karl, Langley, Nigel, Majumdar, Soumyajit, Neupane, Dipesh, Mishra, Sanjay R., Repka, Michael A.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4766117/
https://ncbi.nlm.nih.gov/pubmed/26283197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-015-0389-7
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