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Ultra-High-Throughput Structure-Based Virtual Screening for Small-Molecule Inhibitors of Protein-Protein Interactions

Protein-protein interactions play important roles in virtually all cellular processes, making them enticing targets for modulation by small-molecule therapeutics: specific examples have been well validated in diseases ranging from cancer and autoimmune disorders, to bacterial and viral infections. D...

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Dades bibliogràfiques
Publicat a:J Chem Inf Model
Autors principals: Johnson, David K., Karanicolas, John
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4765363/
https://ncbi.nlm.nih.gov/pubmed/26726827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jcim.5b00572
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