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Modelling local gene networks increases power to detect trans-acting genetic effects on gene expression

Expression quantitative trait loci (eQTL) mapping is a widely used tool to study the genetics of gene expression. Confounding factors and the burden of multiple testing limit the ability to map distal trans eQTLs, which is important to understand downstream genetic effects on genes and pathways. We...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Genome Biol
Prif Awduron: Rakitsch, Barbara, Stegle, Oliver
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4765046/
https://ncbi.nlm.nih.gov/pubmed/26911988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-016-0895-2
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