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Tejaas: reverse regression increases power for detecting trans-eQTLs
Trans-acting expression quantitative trait loci (trans-eQTLs) account for ≥70% expression heritability and could therefore facilitate uncovering mechanisms underlying the origination of complex diseases. Identifying trans-eQTLs is challenging because of small effect sizes, tissue specificity, and a...
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| Vydáno v: | Genome Biol |
|---|---|
| Hlavní autoři: | , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
BioMed Central
2021
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8101255/ https://ncbi.nlm.nih.gov/pubmed/33957961 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-021-02361-8 |
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