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Identification of trans-eQTLs using mediation analysis with multiple mediators
BACKGROUND: Mapping expression quantitative trait loci (eQTLs) has provided insight into gene regulation. Compared to cis-eQTLs, the regulatory mechanisms of trans-eQTLs are less known. Previous studies suggest that trans-eQTLs may regulate expression of remote genes by altering the expression of ne...
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| Publicado en: | BMC Bioinformatics |
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| Autores principales: | , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
BioMed Central
2019
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6440281/ https://ncbi.nlm.nih.gov/pubmed/30925861 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-019-2651-6 |
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