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Modelling local gene networks increases power to detect trans-acting genetic effects on gene expression

Expression quantitative trait loci (eQTL) mapping is a widely used tool to study the genetics of gene expression. Confounding factors and the burden of multiple testing limit the ability to map distal trans eQTLs, which is important to understand downstream genetic effects on genes and pathways. We...

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Bibliografiset tiedot
Julkaisussa:Genome Biol
Päätekijät: Rakitsch, Barbara, Stegle, Oliver
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BioMed Central 2016
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4765046/
https://ncbi.nlm.nih.gov/pubmed/26911988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-016-0895-2
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