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Modelling local gene networks increases power to detect trans-acting genetic effects on gene expression
Expression quantitative trait loci (eQTL) mapping is a widely used tool to study the genetics of gene expression. Confounding factors and the burden of multiple testing limit the ability to map distal trans eQTLs, which is important to understand downstream genetic effects on genes and pathways. We...
Enregistré dans:
| Publié dans: | Genome Biol |
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| Auteurs principaux: | , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
BioMed Central
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4765046/ https://ncbi.nlm.nih.gov/pubmed/26911988 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-016-0895-2 |
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