Cancer Stem Cell Phenotype Is Supported by Secretory Phospholipase A(2) in Human Lung Cancer Cells

BACKGROUND: Lung cancer stem cells (CSCs) are a sub-population of cells that drive growth, invasiveness, and resistance to therapy. Inflammatory eicosanoids are critical to maintain this malignant subpopulation. Secretory phospholipase A(2) group IIa (sPLA(2)) is an important mediator of the growth...

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Udgivet i:Ann Thorac Surg
Main Authors: Bennett, Daine T., Deng, Xin-Sheng, Yu, Jessica A., Bell, Marshall T., Mauchley, David C., Meng, Xianzhong, Reece, T. Brett, Fullerton, David A., Weyant, Michael J.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4764123/
https://ncbi.nlm.nih.gov/pubmed/24928671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.athoracsur.2014.04.044
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