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Group IIa secretory phospholipase expression correlates with group IIa secretory phospholipase inhibition–mediated cell death in K-ras mutant lung cancer cells

OBJECTIVE: There are currently no targeted therapies against lung tumors with oncogenic K-ras mutations that are found in 25% to −40% of lung cancers and are characterized by their resistance to epidermal growth factor receptor inhibitors. The isozyme group IIa secretory phospholipase A(2) (sPLA(2)I...

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Main Authors: Yu, Jessica A., Li, Howard, Meng, Xianzhong, Fullerton, David A., Nemenoff, Raphael A., Mitchell, John D., Weyant, Michael J.
格式: Artigo
語言:Inglês
出版: 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3855847/
https://ncbi.nlm.nih.gov/pubmed/23026567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtcvs.2012.08.064
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