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Group IIa secretory phospholipase expression correlates with group IIa secretory phospholipase inhibition–mediated cell death in K-ras mutant lung cancer cells
OBJECTIVE: There are currently no targeted therapies against lung tumors with oncogenic K-ras mutations that are found in 25% to −40% of lung cancers and are characterized by their resistance to epidermal growth factor receptor inhibitors. The isozyme group IIa secretory phospholipase A(2) (sPLA(2)I...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2012
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3855847/ https://ncbi.nlm.nih.gov/pubmed/23026567 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtcvs.2012.08.064 |
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