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Knockdown of secretory phospholipase A2 IIa reduces lung cancer growth in vitro and in vivo
OBJECTIVE: Group IIa secretory phospholipase A2 (sPLA2 IIa) plays a role in the malignant potential of several epithelial cancers. Nuclear factor kappa B (NF-κB) regulates cancer cell growth and is modulated by phospholipase activity in many cancer cells. We hypothesized that knockdown of sPLA2 in l...
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| Autors principals: | , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3850277/ https://ncbi.nlm.nih.gov/pubmed/23079010 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtcvs.2012.08.003 |
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