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Activating peptides for cellular uptake via polymerization into high density brushes

The utility of peptide therapeutics is thwarted by an inability to enter cells, preventing access to crucial intracellular targets. Herein, we describe a simple and potentially widely applicable solution involving the polymerization of a minimally modified amino acid sequence into a high density bru...

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Detaylı Bibliyografya
Yayımlandı:Chem Sci
Asıl Yazarlar: Blum, Angela P., Kammeyer, Jacquelin K., Gianneschi, Nathan C.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Royal Society of Chemistry 2016
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4763988/
https://ncbi.nlm.nih.gov/pubmed/26925209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5sc03417e
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