Proapoptotic Peptide Brush Polymer Nanoparticles via Photoinitiated Polymerization-Induced Self-Assembly

Herein we report photoinitiated polymerization-induced self-assembly (photo-PISA) of spherical micelles consisting of proapoptotic peptide-polymer amphiphiles. The one-pot synthetic approach yielded micellar nanoparticles at high concentrations and at scale (150 mg/mL) with tunable peptide loadings...

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Bibliographic Details
Published in:Angew Chem Int Ed Engl
Main Authors: Sun, Hao, Cao, Wei, Zang, Nanzhi, Clemons, Tristan D., Scheutz, Georg M., Hu, Ziying, Thompson, Matthew P., Liang, Yifei, Vratsanos, Maria, Zhou, Xuhao, Choi, Wonmin, Sumerlin, Brent S., Stupp, Samuel I., Gianneschi, Nathan C.
Format: Artigo
Language:Inglês
Published: 2020
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7722202/
https://ncbi.nlm.nih.gov/pubmed/32659039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.202006385
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