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Activating peptides for cellular uptake via polymerization into high density brushes
The utility of peptide therapeutics is thwarted by an inability to enter cells, preventing access to crucial intracellular targets. Herein, we describe a simple and potentially widely applicable solution involving the polymerization of a minimally modified amino acid sequence into a high density bru...
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| Pubblicato in: | Chem Sci |
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| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Royal Society of Chemistry
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4763988/ https://ncbi.nlm.nih.gov/pubmed/26925209 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5sc03417e |
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