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Nuclease Resistant DNA via High-Density Packing in Polymeric Micellar Nanoparticle Coronas

Herein, we describe a polymeric micellar nanoparticle capable of rendering nucleic acids resistant to nuclease digestion. This approach relies on utilizing DNA as the polar head group of a DNA-polymer amphiphile in order to assemble well-defined, discrete nanoparticles. Dense packing of DNA in the m...

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Détails bibliographiques
Auteurs principaux: Rush, Anthony M., Thompson, Matthew P., Tatro, Erick T., Gianneschi, Nathan C.
Format: Artigo
Langue:Inglês
Publié: 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3608424/
https://ncbi.nlm.nih.gov/pubmed/23379679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/nn305030g
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