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Nuclease Resistant DNA via High-Density Packing in Polymeric Micellar Nanoparticle Coronas
Herein, we describe a polymeric micellar nanoparticle capable of rendering nucleic acids resistant to nuclease digestion. This approach relies on utilizing DNA as the polar head group of a DNA-polymer amphiphile in order to assemble well-defined, discrete nanoparticles. Dense packing of DNA in the m...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3608424/ https://ncbi.nlm.nih.gov/pubmed/23379679 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/nn305030g |
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