Tle1 tumor suppressor negatively regulates inflammation in vivo and modulates NF-κB inflammatory pathway

Tle1 (transducin-like enhancer of split 1) is a corepressor that interacts with a variety of DNA-binding transcription factors and has been implicated in many cellular functions; however, physiological studies are limited. Tle1-deficient (Tle1(Δ/Δ)) mice, although grossly normal at birth, exhibit sk...

Full description

Saved in:
Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Ramasamy, Selvi, Saez, Borja, Mukhopadhyay, Subhankar, Ding, Daching, Ahmed, Alwiya M., Chen, Xi, Pucci, Ferdinando, Yamin, Rae’e, Wang, Jianfeng, Pittet, Mikael J., Kelleher, Cassandra M., Scadden, David T., Sweetser, David A.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2016
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4763742/
https://ncbi.nlm.nih.gov/pubmed/26831087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1511380113
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items