Tle corepressors are differentially partitioned to instruct CD8(+) T cell lineage choice and identity

Tle/Groucho proteins are transcriptional corepressors interacting with Tcf/Lef and Runx transcription factors, but their physiological roles in T cell development remain unknown. Conditional targeting of Tle1, Tle3 and Tle4 revealed gene dose–dependent requirements for Tle proteins in CD8(+) lineage...

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Detalhes bibliográficos
Publicado no:J Exp Med
Main Authors: Xing, Shaojun, Shao, Peng, Li, Fengyin, Zhao, Xudong, Seo, Wooseok, Wheat, Justin C., Ramasamy, Selvi, Wang, Jianfeng, Li, Xiang, Peng, Weiqun, Yu, Shuyang, Liu, Chengyu, Taniuchi, Ichiro, Sweetser, David A., Xue, Hai-Hui
Formato: Artigo
Idioma:Inglês
Publicado em: Rockefeller University Press 2018
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6080905/
https://ncbi.nlm.nih.gov/pubmed/30045946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20171514
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