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Tcf1 instructs T follicular helper cell differentiation by repressing Blimp1 in response to acute viral infection

Differentiation of T follicular helper (T(FH)) cells is regulated by a complex transcriptional network, with mutually antagonistic Bcl6-Blimp1 as a core regulatory axis. It is well-established that Tcf1 acts upstream of Bcl6 for its optimal induction to program T(FH) cell differentiation. Here we sh...

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Bibliografski detalji
Izdano u:J Immunol
Glavni autori: Shao, Peng, Li, Fengyin, Wang, Jinyong, Chen, Xia, Liu, Chengyu, Xue, Hai-Hui
Format: Artigo
Jezik:Inglês
Izdano: 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6684471/
https://ncbi.nlm.nih.gov/pubmed/31300510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1900581
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