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TLE4 regulation of wnt-mediated inflammation underlies its role as a tumor suppressor in myeloid leukemia
The presence of AML1-ETO (RUNX1-CBF2T1), a fusion oncoprotein resulting from a t(8;21) chromosomal translocation, has been implicated as a necessary but insufficient event in the development of a subset of acute myeloid leukemias (AML). While AML1-ETO prolongs survival and inhibits differentiation o...
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| Publicado no: | Leuk Res |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5266616/ https://ncbi.nlm.nih.gov/pubmed/27486062 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.leukres.2016.07.002 |
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