TLE4 regulation of wnt-mediated inflammation underlies its role as a tumor suppressor in myeloid leukemia

The presence of AML1-ETO (RUNX1-CBF2T1), a fusion oncoprotein resulting from a t(8;21) chromosomal translocation, has been implicated as a necessary but insufficient event in the development of a subset of acute myeloid leukemias (AML). While AML1-ETO prolongs survival and inhibits differentiation o...

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Udgivet i:Leuk Res
Main Authors: Shin, Thomas H., Brynczka, Christopher, Dayyani, Farshid, Rivera, Miguel N., Sweetser, David A.
Format: Artigo
Sprog:Inglês
Udgivet: 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5266616/
https://ncbi.nlm.nih.gov/pubmed/27486062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.leukres.2016.07.002
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