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Integrated in vivo and in vitro nascent chain profiling reveals widespread translational pausing

Although the importance of the nonuniform progression of elongation in translation is well recognized, there have been few attempts to explore this process by directly profiling nascent polypeptides, the relevant intermediates of translation. Such approaches will be essential to complement other app...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Main Authors: Chadani, Yuhei, Niwa, Tatsuya, Chiba, Shinobu, Taguchi, Hideki, Ito, Koreaki
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4763732/
https://ncbi.nlm.nih.gov/pubmed/26831095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1520560113
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