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Integrated in vivo and in vitro nascent chain profiling reveals widespread translational pausing

Although the importance of the nonuniform progression of elongation in translation is well recognized, there have been few attempts to explore this process by directly profiling nascent polypeptides, the relevant intermediates of translation. Such approaches will be essential to complement other app...

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Foilsithe in:Proc Natl Acad Sci U S A
Main Authors: Chadani, Yuhei, Niwa, Tatsuya, Chiba, Shinobu, Taguchi, Hideki, Ito, Koreaki
Formáid: Artigo
Teanga:Inglês
Foilsithe: National Academy of Sciences 2016
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4763732/
https://ncbi.nlm.nih.gov/pubmed/26831095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1520560113
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