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Sustained TNF production by central nervous system infiltrating macrophages promotes progressive autoimmune encephalomyelitis

BACKGROUND: Tumor necrosis factor (TNF) has pleiotropic functions during both the demyelinating autoimmune disease multiple sclerosis (MS) and its murine model experimental autoimmune encephalomyelitis (EAE). How TNF regulates disability during progressive disease remains unresolved. Using a progres...

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書誌詳細
出版年:J Neuroinflammation
主要な著者: Valentin-Torres, Alice, Savarin, Carine, Hinton, David R., Phares, Timothy W., Bergmann, Cornelia C., Stohlman, Stephen A.
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4763407/
https://ncbi.nlm.nih.gov/pubmed/26906225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-016-0513-y
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