Sustained TNF production by central nervous system infiltrating macrophages promotes progressive autoimmune encephalomyelitis

BACKGROUND: Tumor necrosis factor (TNF) has pleiotropic functions during both the demyelinating autoimmune disease multiple sclerosis (MS) and its murine model experimental autoimmune encephalomyelitis (EAE). How TNF regulates disability during progressive disease remains unresolved. Using a progres...

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Detaylı Bibliyografya
Yayımlandı:J Neuroinflammation
Asıl Yazarlar: Valentin-Torres, Alice, Savarin, Carine, Hinton, David R., Phares, Timothy W., Bergmann, Cornelia C., Stohlman, Stephen A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2016
Konular:
Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4763407/
https://ncbi.nlm.nih.gov/pubmed/26906225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-016-0513-y
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