Sustained TNF production by central nervous system infiltrating macrophages promotes progressive autoimmune encephalomyelitis

BACKGROUND: Tumor necrosis factor (TNF) has pleiotropic functions during both the demyelinating autoimmune disease multiple sclerosis (MS) and its murine model experimental autoimmune encephalomyelitis (EAE). How TNF regulates disability during progressive disease remains unresolved. Using a progres...

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Detalhes bibliográficos
Publicado no:J Neuroinflammation
Main Authors: Valentin-Torres, Alice, Savarin, Carine, Hinton, David R., Phares, Timothy W., Bergmann, Cornelia C., Stohlman, Stephen A.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4763407/
https://ncbi.nlm.nih.gov/pubmed/26906225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-016-0513-y
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