Genetic editing of HLA expression in hematopoietic stem cells to broaden their human application

Mismatch of human leukocyte antigens (HLA) adversely impacts the outcome of patients after allogeneic hematopoietic stem-cell transplantation (alloHSCT). This translates into the clinical requirement to timely identify suitable HLA-matched donors which in turn curtails the chances of recipients, esp...

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Detaylı Bibliyografya
Yayımlandı:Sci Rep
Asıl Yazarlar: Torikai, Hiroki, Mi, Tiejuan, Gragert, Loren, Maiers, Martin, Najjar, Amer, Ang, Sonny, Maiti, Sourindra, Dai, Jianliang, Switzer, Kirsten C., Huls, Helen, Dulay, Gladys P., Reik, Andreas, Rebar, Edward J., Holmes, Michael C., Gregory, Philip D., Champlin, Richard E., Shpall, Elizabeth J., Cooper, Laurence J. N.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2016
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4763194/
https://ncbi.nlm.nih.gov/pubmed/26902653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep21757
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