Collaborative Enhancement of Endothelial Targeting of Nanocarriers by Modulating Platelet-Endothelial Cell Adhesion Molecule-1/CD31 Epitope Engagement

Nanocarriers (NCs) coated with antibodies (Abs) to extracellular epitopes of the transmembrane glycoprotein PECAM (platelet endothelial cell adhesion molecule-1/CD31) enable targeted drug delivery to vascular endothelial cells. Recent studies revealed that paired Abs directed to adjacent, yet distin...

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Detalles Bibliográficos
Publicado en:ACS Nano
Autores principales: Chacko, Ann-Marie, Han, Jingyan, Greineder, Colin F., Zern, Blaine J., Mikitsh, John L., Nayak, Madhura, Menon, Divya, Johnston, Ian H., Poncz, Mortimer, Eckmann, David M., Davies, Peter F., Muzykantov, Vladimir R.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2015
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4761649/
https://ncbi.nlm.nih.gov/pubmed/26153796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/nn505672x
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