The conformation of the sarcin/ricin loop from 28S ribosomal RNA.
The sarcin/ricin loop is a highly conserved sequence found in the RNA of all large ribosomal subunits. The cytotoxins alpha-sarcin and ricin both inactivate ribosomes by cleaving a single bond in that loop. Once it has been attacked, ribosomes no longer interact with elongation factors properly, and...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1993
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC47613/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8415744/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.20.9581 |
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