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Peptide Mimics of the Ribosomal P Stalk Inhibit the Activity of Ricin A Chain by Preventing Ribosome Binding

Ricin A chain (RTA) depurinates the sarcin/ricin loop (SRL) by interacting with the C-termini of the ribosomal P stalk. The ribosome interaction site and the active site are located on opposite faces of RTA. The interaction with P proteins allows RTA to depurinate the SRL on the ribosome at physiolo...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Xiao-Ping Li, Jennifer N. Kahn, Nilgun E. Tumer
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: MDPI AG 2018-09-01
Sarja:Toxins
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Linkit:http://www.mdpi.com/2072-6651/10/9/371
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