Thiostrepton inhibits the turnover but not the GTPase of elongation factor G on the ribosome

The region around position 1067 in domain II of 23S rRNA frequently is referred to as the GTPase center of the ribosome. The notion is based on the observation that the binding of the antibiotic thiostrepton to this region inhibited GTP hydrolysis by elongation factor G (EF-G) on the ribosome at the...

ver descrição completa

Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Rodnina, Marina V., Savelsbergh, Andreas, Matassova, Natalia B., Katunin, Vladimir I., Semenkov, Yuri P., Wintermeyer, Wolfgang
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1999
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC22252/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10449736/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.17.9586
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!