The "allosteric three-site model" of elongation cannot be confirmed in a well-defined ribosome system from Escherichia coli.
For the functional role of the ribosomal tRNA exit (E) site, two different models have been proposed. It has been suggested that transient E-site binding of the tRNA leaving the peptidyl (P) site promotes elongation factor G (EF-G)-dependent translocation by lowering the energetic barrier of tRNA re...
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| Publicado no: | Proc Natl Acad Sci U S A |
|---|---|
| Principais autores: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1996
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC37964/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8901554/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.22.12183 |
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