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Thiostrepton inhibits the turnover but not the GTPase of elongation factor G on the ribosome

The region around position 1067 in domain II of 23S rRNA frequently is referred to as the GTPase center of the ribosome. The notion is based on the observation that the binding of the antibiotic thiostrepton to this region inhibited GTP hydrolysis by elongation factor G (EF-G) on the ribosome at the...

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Detaylı Bibliyografya
Asıl Yazarlar: Rodnina, Marina V., Savelsbergh, Andreas, Matassova, Natalia B., Katunin, Vladimir I., Semenkov, Yuri P., Wintermeyer, Wolfgang
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The National Academy of Sciences 1999
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC22252/
https://ncbi.nlm.nih.gov/pubmed/10449736
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