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Role and timing of GTP binding and hydrolysis during EF-G-dependent tRNA translocation on the ribosome
The translocation of tRNA and mRNA through the ribosome is promoted by elongation factor G (EF-G), a GTPase that hydrolyzes GTP during the reaction. Recently, it was reported that, in contrast to previous observations, the affinity of EF-G was much weaker for GTP than for GDP and that ribosome-catal...
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| Hoofdauteurs: | , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
National Academy of Sciences
2006
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1564220/ https://ncbi.nlm.nih.gov/pubmed/16940356 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0606099103 |
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