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Role and timing of GTP binding and hydrolysis during EF-G-dependent tRNA translocation on the ribosome

The translocation of tRNA and mRNA through the ribosome is promoted by elongation factor G (EF-G), a GTPase that hydrolyzes GTP during the reaction. Recently, it was reported that, in contrast to previous observations, the affinity of EF-G was much weaker for GTP than for GDP and that ribosome-catal...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Wilden, Berthold, Savelsbergh, Andreas, Rodnina, Marina V., Wintermeyer, Wolfgang
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2006
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1564220/
https://ncbi.nlm.nih.gov/pubmed/16940356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0606099103
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