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GTP hydrolysis by EF-G synchronizes tRNA movement on small and large ribosomal subunits

Elongation factor G (EF-G) promotes the movement of two tRNAs and the mRNA through the ribosome in each cycle of peptide elongation. During translocation, the tRNAs transiently occupy intermediate positions on both small (30S) and large (50S) ribosomal subunits. How EF-G and GTP hydrolysis control t...

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Detalhes bibliográficos
Main Authors: Holtkamp, Wolf, Cunha, Carlos E, Peske, Frank, Konevega, Andrey L, Wintermeyer, Wolfgang, Rodnina, Marina V
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4193938/
https://ncbi.nlm.nih.gov/pubmed/24614227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/embj.201387465
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