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Dual use of GTP hydrolysis by elongation factor G on the ribosome

Elongation factor G (EF-G) is a GTPase that catalyzes tRNA and mRNA translocation during the elongation cycle of protein synthesis. The GTP-bound state of the factor on the ribosome has been studied mainly with non-hydrolyzable analogs of GTP, which led to controversial conclusions about the role of...

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Publicado en:Translation (Austin)
Autores principales: Cunha, Carlos E., Belardinelli, Riccardo, Peske, Frank, Holtkamp, Wolf, Wintermeyer, Wolfgang, Rodnina, Marina V.
Formato: Artigo
Lenguaje:Inglês
Publicado: Taylor & Francis 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4718068/
https://ncbi.nlm.nih.gov/pubmed/26824016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/trla.24315
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