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Dual use of GTP hydrolysis by elongation factor G on the ribosome

Elongation factor G (EF-G) is a GTPase that catalyzes tRNA and mRNA translocation during the elongation cycle of protein synthesis. The GTP-bound state of the factor on the ribosome has been studied mainly with non-hydrolyzable analogs of GTP, which led to controversial conclusions about the role of...

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Podrobná bibliografie
Vydáno v:Translation (Austin)
Hlavní autoři: Cunha, Carlos E., Belardinelli, Riccardo, Peske, Frank, Holtkamp, Wolf, Wintermeyer, Wolfgang, Rodnina, Marina V.
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4718068/
https://ncbi.nlm.nih.gov/pubmed/26824016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/trla.24315
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