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Crystal structure of the ribosomal RNA domain essential for binding elongation factors

The structure of a 29-nucleotide RNA containing the sarcin/ricin loop (SRL) of rat 28 S rRNA has been determined at 2.1 Å resolution. Recognition of the SRL by elongation factors and by the ribotoxins, sarcin and ricin, requires a nearly universal dodecamer sequence that folds into a G-bulged cross-...

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Detalhes bibliográficos
Main Authors: Correll, Carl C., Munishkin, Alexander, Chan, Yuen-Ling, Ren, Zhong, Wool, Ira G., Steitz, Thomas A.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 1998
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC24837/
https://ncbi.nlm.nih.gov/pubmed/9811818
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