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Dementia-linked amyloidosis is associated with brain protein deamidation as revealed by proteomic profiling of human brain tissues
BACKGROUND: Aggregation of malformed proteins is a key feature of many neurodegenerative diseases, but the mechanisms that drive proteinopathy in the brain are poorly understood. We aimed to characterize aggregated proteins in human brain tissues affected by dementia. RESULTS: To characterize amyloi...
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| Pubblicato in: | Mol Brain |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BioMed Central
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4759965/ https://ncbi.nlm.nih.gov/pubmed/26892330 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13041-016-0200-z |
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