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Dissecting the self-assembly kinetics of multimeric pore-forming toxins

Pore-forming toxins are ubiquitous cytotoxins that are exploited by both bacteria and the immune response of eukaryotes. These toxins kill cells by assembling large multimeric pores on the cell membrane. However, a quantitative understanding of the mechanism and kinetics of this self-assembly proces...

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Publicat a:J R Soc Interface
Autors principals: Lee, A. A., Senior, M. J., Wallace, M. I., Woolley, T. E., Griffiths, I. M.
Format: Artigo
Idioma:Inglês
Publicat: The Royal Society 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4759788/
https://ncbi.nlm.nih.gov/pubmed/26763328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsif.2015.0762
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