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X-ray and Cryo-electron Microscopy Structures of Monalysin Pore-forming Toxin Reveal Multimerization of the Pro-form

β-Barrel pore-forming toxins (β-PFT), a large family of bacterial toxins, are generally secreted as water-soluble monomers and can form oligomeric pores in membranes following proteolytic cleavage and interaction with cell surface receptors. Monalysin has been recently identified as a β-PFT that con...

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Publicat a:J Biol Chem
Autors principals: Leone, Philippe, Bebeacua, Cecilia, Opota, Onya, Kellenberger, Christine, Klaholz, Bruno, Orlov, Igor, Cambillau, Christian, Lemaitre, Bruno, Roussel, Alain
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4505573/
https://ncbi.nlm.nih.gov/pubmed/25847242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.646109
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