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Rapid Assembly of a Multimeric Membrane Protein Pore
We have observed the assembly of the staphylococcal pore-forming toxin α-hemolysin using single-molecule fluorescence imaging. Surprisingly, assembly from the monomer to the complete heptamer is extremely rapid, occurring in <5 ms. No lower order oligomeric intermediates are detected. Monte Carlo...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Biophysical Society
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3297801/ https://ncbi.nlm.nih.gov/pubmed/22261056 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2011.09.054 |
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