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Redirecting Pore Assembly of Staphylococcal α-Hemolysin by Protein Engineering
[Image: see text] α-Hemolysin (αHL), a β-barrel pore-forming toxin (βPFT), is secreted as a water-soluble monomer by Staphylococcus aureus. Upon binding to receptors on target cell membranes, αHL assembles to form heptameric membrane-spanning pores. We have previously engineered αHL to create a prot...
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| Publicado no: | ACS Cent Sci |
|---|---|
| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Chemical Society
2019
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6487460/ https://ncbi.nlm.nih.gov/pubmed/31041382 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acscentsci.8b00910 |
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