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Soluble Oligomers of the Pore-forming Toxin Cytolysin A from Escherichia coli Are Off-pathway Products of Pore Assembly

The α-pore-forming toxin Cytolysin A (ClyA) is responsible for the hemolytic activity of various Escherichia coli and Salmonella enterica strains. Soluble ClyA monomers spontaneously assemble into annular dodecameric pore complexes upon contact with membranes or detergent. At ClyA monomer concentrat...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Roderer, Daniel, Benke, Stephan, Schuler, Benjamin, Glockshuber, Rudi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4786705/
https://ncbi.nlm.nih.gov/pubmed/26757820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.700757
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