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A Non-classical Assembly Pathway of Escherichia coli Pore-forming Toxin Cytolysin A

Cytolysin A (ClyA) is an α-pore forming toxin from pathogenic Escherichia coli (E. coli) and Salmonella enterica. Here, we report that E. coli ClyA assembles into an oligomeric structure in solution in the absence of either bilayer membranes or detergents at physiological temperature. These oligomer...

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Hlavní autoři: Fahie, Monifa, Romano, Fabian B., Chisholm, Christina, Heuck, Alejandro P., Zbinden, Mark, Chen, Min
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2013
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3829417/
https://ncbi.nlm.nih.gov/pubmed/24019520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.475350
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