Somatic mtDNA variation is an important component of Parkinson's disease

There is a growing body of evidence linking mitochondrial dysfunction, mediated either through inherited mitochondrial DNA (mtDNA) variation or mitochondrial proteomic deficit, to Parkinson's disease (PD). Yet, despite this, the role of somatic mtDNA point mutations and specifically point-mutat...

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Dettagli Bibliografici
Pubblicato in:Neurobiol Aging
Autori principali: Coxhead, Jonathan, Kurzawa-Akanbi, Marzena, Hussain, Rafiqul, Pyle, Angela, Chinnery, Patrick, Hudson, Gavin
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2016
Soggetti:
Genetic Report Abstract
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4759607/
https://ncbi.nlm.nih.gov/pubmed/26639157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2015.10.036
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