Somatic mtDNA variation is an important component of Parkinson's disease

There is a growing body of evidence linking mitochondrial dysfunction, mediated either through inherited mitochondrial DNA (mtDNA) variation or mitochondrial proteomic deficit, to Parkinson's disease (PD). Yet, despite this, the role of somatic mtDNA point mutations and specifically point-mutat...

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Podrobná bibliografie
Vydáno v:Neurobiol Aging
Hlavní autoři: Coxhead, Jonathan, Kurzawa-Akanbi, Marzena, Hussain, Rafiqul, Pyle, Angela, Chinnery, Patrick, Hudson, Gavin
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2016
Témata:
Genetic Report Abstract
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4759607/
https://ncbi.nlm.nih.gov/pubmed/26639157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2015.10.036
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