Reduced mitochondrial DNA copy number is a biomarker of Parkinson's disease

Like any organ, the brain is susceptible to the march of time and a reduction in mitochondrial biogenesis is a hallmark of the aging process. In the largest investigation of mitochondrial copy number in Parkinson's disease (PD) to date and by using multiple tissues, we demonstrate that reduced...

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Bibliographic Details
Published in:Neurobiol Aging
Main Authors: Pyle, Angela, Anugrha, Haidyan, Kurzawa-Akanbi, Marzena, Yarnall, Alison, Burn, David, Hudson, Gavin
Format: Artigo
Language:Inglês
Published: Elsevier 2016
Subjects:
Genetic Report Abstract
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4759605/
https://ncbi.nlm.nih.gov/pubmed/26639155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2015.10.033
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