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Activated ErbB3 Translocates to the Nucleus via Clathrin-independent Endocytosis, Which Is Associated with Proliferating Cells

Members of the receptor tyrosine kinase family (RTK) have been shown to be present in the nucleus of cells; however, the mechanisms underlying their trafficking to the nucleus, and their relevance once there are poorly understood. In the present study, we focus on the RTK ErbB3 and elucidate the mec...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Reif, Raymond, Adawy, Alshaimaa, Vartak, Nachiket, Schröder, Jutta, Günther, Georgia, Ghallab, Ahmed, Schmidt, Marcus, Schormann, Wiebke, Hengstler, Jan G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4759164/
https://ncbi.nlm.nih.gov/pubmed/26719328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.686782
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