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Interleukin-35 limits anti-tumor immunity

Regulatory T (Treg) cells pose a major barrier to effective anti-tumor immunity. Although Treg cell depletion enhances tumor rejection, the ensuing autoimmune sequelae limits its utility in the clinic and highlights the need for limiting Treg cell activity within the tumor microenvironment. Interleu...

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Bibliografski detalji
Izdano u:Immunity
Glavni autori: Turnis, Meghan E., Sawant, Deepali V., Szymczak-Workman, Andrea L., Andrews, Lawrence P., Delgoffe, Greg M., Yano, Hiroshi, Beres, Amy J., Vogel, Peter, Workman, Creg J., Vignali, Dario A. A.
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4758699/
https://ncbi.nlm.nih.gov/pubmed/26872697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2016.01.013
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