Interleukin-35 limits anti-tumor immunity

Regulatory T (Treg) cells pose a major barrier to effective anti-tumor immunity. Although Treg cell depletion enhances tumor rejection, the ensuing autoimmune sequelae limits its utility in the clinic and highlights the need for limiting Treg cell activity within the tumor microenvironment. Interleu...

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Bibliografiske detaljer
Udgivet i:Immunity
Main Authors: Turnis, Meghan E., Sawant, Deepali V., Szymczak-Workman, Andrea L., Andrews, Lawrence P., Delgoffe, Greg M., Yano, Hiroshi, Beres, Amy J., Vogel, Peter, Workman, Creg J., Vignali, Dario A. A.
Format: Artigo
Sprog:Inglês
Udgivet: 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4758699/
https://ncbi.nlm.nih.gov/pubmed/26872697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2016.01.013
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