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Accelerated pericyte degeneration and blood–brain barrier breakdown in apolipoprotein E4 carriers with Alzheimer’s disease

The blood–brain barrier (BBB) limits the entry of neurotoxic blood-derived products and cells into the brain that is required for normal neuronal functioning and information processing. Pericytes maintain the integrity of the BBB and degenerate in Alzheimer’s disease (AD). The BBB is damaged in AD,...

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Bibliografski detalji
Izdano u:J Cereb Blood Flow Metab
Glavni autori: Halliday, Matthew R, Rege, Sanket V, Ma, Qingyi, Zhao, Zhen, Miller, Carol A, Winkler, Ethan A, Zlokovic, Berislav V
Format: Artigo
Jezik:Inglês
Izdano: SAGE Publications 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4758554/
https://ncbi.nlm.nih.gov/pubmed/25757756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2015.44
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