Pericyte loss influences Alzheimer-like neurodegeneration in mice

Pericytes are cells in the blood–brain barrier that degenerate in Alzheimer’s disease (AD), a neurological disorder associated with neurovascular dysfunction, abnormal elevation of amyloid β-peptide (Aβ), tau pathology and neuronal loss. Whether pericyte degeneration can influence AD-like neurodegen...

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Main Authors: Sagare, Abhay P., Bell, Robert D., Zhao, Zhen, Ma, Qingyi, Winkler, Ethan A., Ramanathan, Anita, Zlokovic, Berislav V.
Format: Artigo
Jezik:Inglês
Izdano: Nature Pub. Group 2013
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3945879/
https://ncbi.nlm.nih.gov/pubmed/24336108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms3932
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