Blood–spinal cord barrier breakdown and pericyte reductions in amyotrophic lateral sclerosis

The blood–brain barrier and blood–spinal cord barrier (BSCB) limit the entry of plasma components and erythrocytes into the central nervous system (CNS). Pericytes play a key role in maintaining blood–CNS barriers. The BSCB is damaged in patients with amyotrophic lateral sclerosis (ALS). Moreover, t...

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Détails bibliographiques
Auteurs principaux: Winkler, Ethan A., Sengillo, Jesse D., Sullivan, John S., Henkel, Jenny S., Appel, Stanley H., Zlokovic, Berislav V.
Format: Artigo
Langue:Inglês
Publié: Springer-Verlag 2012
Sujets:
Original Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3535352/
https://ncbi.nlm.nih.gov/pubmed/22941226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-012-1039-8
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