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Blood–spinal cord barrier breakdown and pericyte reductions in amyotrophic lateral sclerosis

The blood–brain barrier and blood–spinal cord barrier (BSCB) limit the entry of plasma components and erythrocytes into the central nervous system (CNS). Pericytes play a key role in maintaining blood–CNS barriers. The BSCB is damaged in patients with amyotrophic lateral sclerosis (ALS). Moreover, t...

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Detalhes bibliográficos
Main Authors: Winkler, Ethan A., Sengillo, Jesse D., Sullivan, John S., Henkel, Jenny S., Appel, Stanley H., Zlokovic, Berislav V.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3535352/
https://ncbi.nlm.nih.gov/pubmed/22941226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-012-1039-8
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