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Blood–spinal cord barrier breakdown and pericyte reductions in amyotrophic lateral sclerosis

The blood–brain barrier and blood–spinal cord barrier (BSCB) limit the entry of plasma components and erythrocytes into the central nervous system (CNS). Pericytes play a key role in maintaining blood–CNS barriers. The BSCB is damaged in patients with amyotrophic lateral sclerosis (ALS). Moreover, t...

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Bibliografiske detaljer
Main Authors: Winkler, Ethan A., Sengillo, Jesse D., Sullivan, John S., Henkel, Jenny S., Appel, Stanley H., Zlokovic, Berislav V.
Format: Artigo
Sprog:Inglês
Udgivet: Springer-Verlag 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3535352/
https://ncbi.nlm.nih.gov/pubmed/22941226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-012-1039-8
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