Blood–spinal cord barrier breakdown and pericyte reductions in amyotrophic lateral sclerosis

The blood–brain barrier and blood–spinal cord barrier (BSCB) limit the entry of plasma components and erythrocytes into the central nervous system (CNS). Pericytes play a key role in maintaining blood–CNS barriers. The BSCB is damaged in patients with amyotrophic lateral sclerosis (ALS). Moreover, t...

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Main Authors: Winkler, Ethan A., Sengillo, Jesse D., Sullivan, John S., Henkel, Jenny S., Appel, Stanley H., Zlokovic, Berislav V.
Format: Artigo
Jezik:Inglês
Izdano: Springer-Verlag 2012
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Original Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3535352/
https://ncbi.nlm.nih.gov/pubmed/22941226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-012-1039-8
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